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Book Introduction
CANINE MYXOMATOUS MITRAL VALVE DISEASE (CHRONIC MITRAL VALVE INSUFFICIENCY)
Canine myxomatous mitral valve disease is the definitive, all-in-one resource for understanding and managing the most prevalent acquired heart disease in dogs.
Authored by Dr. Changbaig Hyun &; Yong-Wei Hung, a world-renowned authority on veterinary cardiology and interventional cardiac therapy, this comprehensive textbook bridges the gap between foundational cardiovascular science and cutting-edge clinical practice.
The book provides an in-depth, evidence-based review of the pathology and progression of myxomatous mitral valve disease (MMVD), detailing current diagnostic methodologies, including advanced echocardiography and cardiac biomarkers. Crucially, it offers clear, systematic treatment guidelines for all stages of the disease, from asymptomatic to refractory heart failure.
With dedicated chapters on practical case studies and the latest interventional, surgical, and pharmaceutical therapeutics, this volume is an essential guide for veterinary practitioners, specialists, residents, and advanced students seeking to master the complexities of MMVD and significantly improve long-term outcomes for their canine patients.
Preface
Over the past several decades, my career has been dedicated to advancing the field of veterinary cardiology, with a particular focus on the profound challenges posed by myxomatous mitral valve disease (MMVD). This degenerative disease, often a silent threat, remains the leading cause of heart failure in our small canine companions. It has been my enduring professional mission to contribute to better diagnostic clarity and more effective treatment options, including the development of new interventional and surgical therapies.
This textbook, Canine Myxomatous Mitral Valve Disease, is the culmination of my clinical experience, research findings, and years spent educating countless students and veterinarians both domestically and internationally.
My primary goal in writing this book is to provide practitioners with a single, comprehensive resource—a guide that systematically covers the fundamental anatomy, pharmacologic strategies, and the latest advancements in interventional and surgical management. I hope this volume not only deepens your understanding of MMVD’s complexities but also serves as an immediately practical reference to enhance the quality of care and improve the longevity of your patients.
I extend my sincere gratitude to co-author Dr. Yong-Wei Hung, my colleagues, students, and, most importantly, the dedicated owners who entrust their beloved companions to our care.
May this book serve as a valuable tool in our shared commitment to veterinary excellence.
Dr. Changbaig Hyun, DVM, PhD
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Book Introduction iii
Preface v
About the Author vii
CHAPTER 01 | Basic Structure and Function of the Cardiovascular System 1
1.1 Basic Anatomy of the Cardiovascular System 1
Pericardium 1
Lungs 1
Heart 2
Cardiac Blood Vessels 8
Cardiac Conduction System 9
1.2 Function of the Cardiovascular System 11
Cardiovascular Circulation 11
Cardiac Cycle 14
Cardiac Contraction and Relaxation 16
Cardiovascular Regulation 18
Cardiac Conduction Pathway 22
CHAPTER 02 | Therapeutic Strategies and Medications for Heart Failure in Small Animals 27
2.1 Medications Used in Heart Failure 28
Diuretics 28
RAAS Blockers (Renin-Angiotensin-Aldosterone System Blockers) 32
Vasodilators 34
Inotropes 39
Beta-Blockers 43
Antiarrhythmics 44
Anticoagulants/Thrombolytics 46
2.2 Nutritional Therapy for Heart Disease 46
Sodium Restriction 47
Protein 48
Potassium 49
Vitamins 49
Antioxidants 50
2.3 Treatment Strategies for Heart Failure (American College of Veterinary Internal Medicine Guidelines) 50
Strength of Recommendation 53
Strength of Evidence 54
Diagnosis and Treatment Guidelines 54
Problems with the ACVIM Guidelines 63
CHAPTER 03 || Myxomatous mitral valve disease 67
3.1 Introduction 67
3.2 Pathogenesis 69
3.3 Clinical Findings 70
3.4 Diagnosis 73
3.5 Treatment and Prognosis 79
3.6 Complications that Worsen the Progression of Heart Valve Disease 80
3.7 Systemic Complications Due to Heart Valve Disease 83
Cardiorenal Syndrome (CRS) 83
Pancreatitis 86
3.8 Echocardiographic Diagnostic Guidelines for Mitral Valve Insufficiency Patients 87
3.9 Diagnostic guideline for determining the severity of mitral valve disease 105
CHAPTER 04 || Case Studies 111
▶CASE 1 111
Patient Information 111
History and Physical Examination 111
Diagnostic Tests 111
Treatment and Patient Monitoring 116
Case Discussion 117
▶CASE 2 121
Patient Information 121
Physical Examination and Phonocardiogram 121
Diagnostic Tests 121
Treatment and Patient Monitoring 126
Case Discussion 126
▶CASE 3 130
Patient Information 130
Physical Examination 130
Diagnostic Tests 130
Treatment and Patient Monitoring 131
Case Discussion 135
▶CASE 4 139
Patient Information 139
Physical Examination 139
Diagnostic Tests 139
Treatment and Patient Observation 142
Case Discussion 146
▶CASE 5 149
Patient Information 149
Physical Examination and Phonocardiography 149
Diagnostic Tests 149
Treatment and Patient Observation 151
Case Discussion 153
▶CASE 6 Mitral Regurgitation - Transcatheter Edge-to-Edge Mitral Valve Repair (TEER) with V-clamp 155
Patient Information 155
Treatment and Patient Monitoring 157
Discussion 159
CHAPTER 05 || New Medical and Surgical Therapeutics 163
5.1 New Medical Therapeutics and Approaches 163
New Medications and New Findings 163
5.2 Drug Trials 171
5.3 New Surgical Therapeutics and Approaches 174
New Cardiac Interventions 174
New Hybrid Therapies 180
New Surgical Therapies 183
Appendix
Imaging Diagnosis Guidelines for Myxomatous Mitral Valve Disease 187
Chest Radiographic Indicators 187
Key Echocardiographic Indicators Used by the Author 190
Index 199
| 도서명 | Canine Myxomatous Mitral Valve Disease (개 이첨판 영문판) | 저자, 역자 | 현창백 외 1인 지음 |
|---|---|---|---|
| 출판사 | 범문에듀케이션 | 크기 | 188 x 257 mm |
| 표지, 쪽수 | 페이퍼백 | 220 쪽 | 제품구성 | 낱권 |
| 출간일 | 2025년 11월 01일 | 내용 및 목차 | 상품 정보 및 본문 기재 |
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